Additional Iodide Therapy Not Required

is evaluation of hepatitis a immunity required or not?

Enhancers not required

Laboratory mice with over half a megabase of DNA upstream of their Myc gene removed still thrive in the absence of stress.

Rat sodium iodide symporter for radioiodide therapy of cancer.

Design and development of new approaches for targeted radiotherapy of cancer and improvement of therapeutic index by more local radiation therapy are very important issues. Adenovirus-mediated delivery of the sodium iodide symporter (NIS) gene to cancer cells is a powerful technique to concentrate lethal radiation in tumor cells and eradicate tumors with increased therapeutic index. A replicati...

Radioisotope concentrator gene therapy using the sodium/iodide symporter gene.

We demonstrate a novel method of concentrating radiation for tumor imaging or killing. The rat sodium/iodide symporter gene (rNIS) was cloned into a retroviral vector for transfer into cancer cells to mimic the iodide uptake of thyroid follicular cells. In vitro iodide transport shows that the symporter functions similarly in rNIS-transduced tumor cells and rat thyroid follicular cells. rNIS-tr...

ARCTIC: Additional proof against antiplatelet adjusted therapy

INTRODUCTION The prognostic value of high platelet reactivity during treatment with aspirin and/or thienopyridine has been demonstrated repeatedly, leading to the rationale for individualized antiplatelet therapy. Bedside tests have previously been used as screening tools to select patients with a poor response to clopidogrel in order to evaluate different treatments. However, conflicting resul...